Impact of the hypercaloric food on the morphological functional state of the liver pregnant rats

Abstract

The study involved examination of morphofunctional state of the liver in 7 rats receiving an unbalanced diet with an excess of carbohydrates and fats during pregnancy, and 6 rats in the control group. Morphological changes in the organ in rats of the 2nd group included discomplexation of lamino-radial structure, protein dystrophy of hepatocytes, increased regenerative activity of the liver, and enhanced conduction velocity in liver tissue. Functional disorders were manifested in the development of disproteinemia, hyperlipidemia, hyperglycemia and hyperketonemia. This indicated a risk of developing liver fibrosis, fatty hepatosis, and type 2 diabetes in the animals.