Current status of development of vaccines against hiv- infection
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How to Cite

Kovalenko, N., & Chernikova , L. (2020). Current status of development of vaccines against hiv- infection. Experimental and Clinical Medicine, 70(1), 89-94. Retrieved from https://ecm.knmu.edu.ua/article/view/477

Abstract

The article analyzes the literature aiming the evolution of problems and prospects in the use of different types of vaccines for the HIV-infection prevention. The questions of the study and the development of immunogens capable to induce different links of immune response and to generate protective immunity are elucidated. The results of the research aimed at studying the spatial structure of the HIV envelope protein epitopes and design of vaccines that would present effectively these epitopes to the immune system are considered. The data of vector and genetic engineering vaccines tests and their mechanism of action due to the induction of broadly neutralizing antibodies have been analyzed.
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