Keywords
connective tissue
pathogenetic mechanisms
autoimmune dysfunction
comorbidity
How to Cite
Abstract
The data are given concerning the retrospective analysis of clinical course, age characteristics, presence of comorbididity in patients with ankylosing spondyloarthritis (AS) that is one of the example of connective tissue (CT) diseases. The authors have shown that comorbidity combination in case of AS should be considered as a result of the whole CT involvement into the pathogenesis as well as all launches of the body's resistance failure. The authors stressed that suppressor lymphocytes activity depression and cytotoxic effects activation are the common mechanism of autoimmune complications in patients with the investigated pathology. The authors concluded about the pathophysiological background of pharmacological drugs using that improve CT nutrition in complex treatment of patients with AS.
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