Patomorfologycal changes of liver and biochemical changes of whey of blood are at acute alcoholic hepatitis in the conditions of experiment
Vol 71 No 2 (2016), Proceedings of the VII National Congress of Pathophysiologists of Ukraine
Vol 71 No 2 (2016)

Patomorfologycal changes of liver and biochemical changes of whey of blood are at acute alcoholic hepatitis in the conditions of experiment

Proceedings of the VII National Congress of Pathophysiologists of Ukraine
Published August 26, 2020
N.A. Rykalo
Vinnytsia National Medical University named after M.I. Pyrohova
I.V. Romanenko
Vinnytsia National Medical University named after M.I. Pyrohova
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Keywords

acute alcoholic hepatitis
experimental model
morphological changes
rats

How to Cite

Rykalo, N., & Romanenko, I. (2020). Patomorfologycal changes of liver and biochemical changes of whey of blood are at acute alcoholic hepatitis in the conditions of experiment. Experimental and Clinical Medicine, 71(2), 156-160. Retrieved from https://ecm.knmu.edu.ua/article/view/684
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Abstract

The article describes the morphological changes of the liver in experimental acute alcoholic hepatitis, which was simulated by injecting rats of a 40% solution of ethanol for seven days, found multiple intracellular the deposition of neutral fats in hepatocytes. Given significant changes of the biochemical markers of the syndrome of cholestasis and cytolysis of hepatocytes, committed changes protein synthetical function of liver and changes in liver metabolism during experimental acute alcoholic hepatitis. Morphologically and biochemically identified dose-dependent effects of a 40% solution of ethanol on the organism of laboratory animals, set it and sublethal lethal dose for the rat organism

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