Metabolic and morphological signs of reduced caries-resistance in offspring of hypokinetic mothers
Vol 71 No 2 (2016), Proceedings of the VII National Congress of Pathophysiologists of Ukraine
Vol 71 No 2 (2016)

Metabolic and morphological signs of reduced caries-resistance in offspring of hypokinetic mothers

Proceedings of the VII National Congress of Pathophysiologists of Ukraine
Published August 12, 2020
М.S. Baranova
Kharkiv National Medical University
T.V. Gorbach
Kharkiv National Medical University
G.I. Gubina-Vakulyk
Kharkiv National Medical University
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Keywords

mother's hypokinesia
total protein
inorganic components descendants of teeth
macroscopic
microscopy descendants teeth

How to Cite

BaranovaМ., Gorbach, T., & Gubina-Vakulyk , G. (2020). Metabolic and morphological signs of reduced caries-resistance in offspring of hypokinetic mothers . Experimental and Clinical Medicine, 71(2), 26-30. Retrieved from https://ecm.knmu.edu.ua/article/view/638
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Abstract

In order to identify experimentally metabolic and morphological signs of decay instability in offspring. It were studied the content of total protein, Ca, Mg in the blood of descendants of females who were one month before mating and during pregnancy in hypokinesia conditions, as well as the content of Ca, Mg in the dental hard tissues. On gross examination the frequency of carious affection was determined. Using computer images of microspeciements, determine the amount of RNA in the cytoplasm and the intensity of the luminescence of type I collagen in dentin of teeth in rats-offspring were made. It is found that the hypokinesia of females led to reduced concentrations of calcium, magnesium, total proteins in the serum of offspring in comparison with the levels of the control group. Deficiency of calcium and magnesium in the blood leads to the reduction of enamel mineralization in young rats in comparison to control group. It was noted the number of dentinal tubules is decreased and a wider lumen of the tubules are formed. In the young descendants on the background of dentinal tubules and odontoblasts hypoplasia a compensatory increase in RNA content in the cytoplasm of the odontoblast processes and in the average content of collagen in the walls of the dentinal tubules are observed. Hypoplastic dentin, hard tissue desaturation of Ca and Mg explains susceptibility to caries in experimental animals.
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