Experience in determining polymorphism of the SLCO1B1 gene in patients with hyperlipidemia
PDF (Українська)

Keywords

pharmacogenetic testing
hyperlipidemia
polymorphism of the SLCO1B1 gene

How to Cite

Ye.O. Maznichenko, Y., & Yakimenko, O. (2020). Experience in determining polymorphism of the SLCO1B1 gene in patients with hyperlipidemia. Experimental and Clinical Medicine, 78(1), 41-45. Retrieved from https://ecm.knmu.edu.ua/article/view/358

Abstract

It was studied the prevalence of polymorphism of the SLCO1B1 gene in patients multiprofile medical center of University clinic № 1. As a result of the study, there were identified 70 (55.1%) carriers of the "wild" type c.521TT; 47 (37%) genotype c.5221T and 10 (7.9%) of patients with homozygous (c.521CS) carriage of the allelic variant of SLCO1B1. An algorithm has been developed for individual selection of the maximum dose of statin and recommended for practical use by experts of the European Science Foundation.
PDF (Українська)

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