Keywords
stable exertional angina pectoris
endothelium-vascular dysfunction
pentoxifillin amlodipine besilat
How to Cite
Abstract
There were examined 45 patients with chronic pulmonary heart and stable exertional angina pectoris of III functional class. All of them were treated by complex therapy included pentoxifillin in a dose of 600 mg per day, 25 of them (main group) in addition received amlodipine besilat. The rates of hemodynamics, nitric oxide, endotheline-1, cytokines and platelet aggregation were investigated. After treatment defined decrease rate of endotheline-1, interleukin-1β, interleukin-6, tumor necrosis factor-α, platelet aggregation capacity and increase of interleukin-4 and nitric oxide. The more positive laboratory-clinical dynamics were in the main group.References
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