Keywords
PRP-therapy
permanent orthodontic technique
How to Cite
Abstract
The effect of PRP-therapy on the state of the vessels of the microvasculature was determined using invariable orthodontic appliances (FOAs). The experiments were carried out on 32 male rabbits of the Dutch breed aged 9 months, which were evenly distributed into four groups: control and experimental groups (I, Il, Ill), 8 animals each. It has been established that treatment with FOAs leads to deterioration of the microcirculatory bed vessels, the development of ischemia and necrosis of the oral mucosa. The use of antibacterial drugs against the background of FOAs leads to a weakly pronounced effect, which develops quite late (on the 20th day in the studied group of rabbits). The most effective method of treatment is the use of PRP-therapy with a pronounced, strong and long-term effect from the very first days with a minimum of contraindications to the procedure.
Keywords: microcirculatory bed, PRP-therapy, permanent orthodontic technique.
References
Reichert, I., Figel, Р., Wmchester, L. (2014). Orthodontic treatment of anterior ореn bite: а review article – is surgery always necessary? Oral Maxillofac Surg., 18(3), 271-277. DOI: 10.1007/s10006-013-0430-5. PMID: 23949448.
Jiang, Q., Li, J., Mei, L., Du, J., Levrini, L., Abbate, G. M., et al. (2018). Periodontal health during orthodontic treatment with clear aligners and fixed appliances: A meta-analysis. J Am Dent Assoc., 149(8), 712-720.e12. DOI: 10.1016/j.adaj.2018.04.010. PMID: 29921415.
Pisani, L., Bonaccorso, L., Fastuca, R., Spena, R., Lombardo, L., Caprioglio, A. (2016). Systematic review for orthodontic and orthopedic treatments for anterior open bite in the mixed dentition. Prog Orthod., 17(1), 28. DOI: 10.1186/s40510-016-0142-0. PMID: 27615261. PMCID: PMC5027197.
Batista, K. B., Thiruvenkatachari, B., Harrison, J. E., O'Brien, K. D. (2018). Orthodontic treatment for prominent upper front teeth (Class II malocclusion) in children and adolescents. Cochrane Database Syst Rev., (13), 3. DOI: 10.1002/14651858.CD003452.pub4. PMID: 29534303. PMCID: PMC6494411.
Kirschneck, C., Christl, J. J., Reicheneder, C., Proff, P. (2016). Efficacy of fluoride varnish for preventing white spot lesions and gingivitis during orthodontic treatment with fixed appliances-a prospective randomized controlled trial. Clin Oral Investig, 20(9), 2371-2378. DOI: 10.1007/s00784-016-1730-6. PMID: 26832780.
Manuelli, M., Marcolina, M., Nardi, N., Bertossi, D., et al. (2019). Oral mucosal complications in orthodontic treatment. Minerva Stomatol., 68(2), 84-88. DOI: 10.23736/S0026-4970.18.04127-4. PMID: 30854838.
Buckley, J. G., Jones, M. L., Hill, M., Sugar, A. W. (1999). An evaluation of the changes in maxillary pulpal blood flow associated with orthognathic surgery. Br J Orthod., 26(1), 39-45, DOI: 10.1093/ortho/26.1.39. PMID: 10333886.
Miron, R. J., Zucchelli, G., Pikos, M. A., Salama, M., et al. (2017). Use of platelet-rich fibrin in regenerative dentistry: a systematic review. Clin OralInvestig, 21(6), 1913-1927, DOI: 10.1007/ s00784-017-2133-z, PMID: 28551729.
Shah, R., Triveni, M. G., Thomas, R., Mehta, D. S. (2017). An Update on the Protocols and Biologic Actions of Platelet Rich Fibrin in Dentistry. Eur J Prosthodont Restor Dent, 25(2), 64-72, DOI: 10.1922/EJPRD_01690Shah09. PMID: 28590091.
Simonpieri, A., Del Corso, M., Vervelle, A., Jimbo, R. et al. (2012). Current knowledge and perspectives for the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in oral and maxillofacial surgery part 2: Bone graft, implant and reconstructive surgery. Curr Pharm Biotechnol, 13(7), 1231¬1256, DOI: 10.2174/138920112800624472, PMID: 21740370.
Ulusoy, A. T., Turedi, I., Cimen, M., Cehreli, Z. C. (2019). Evaluation of Blood Clot, Platelet-rich Plasma, Platelet-rich Fibrin, and Platelet Pellet as Scaffolds in Regenerative Endodontic Treatment: A Prospective Randomized Trial. J Endod, 45(5), 560-566. DOI: 10.1016/j.joen.2019.02.002. PMID: 30935618.
Miron, R. J., Fujioka-Kobayashi, M., Hernandez, M., Kandalam, U., et al. (2017). Injectable platelet rich fibrin (i-PRF): opportunities in regenerative dentistry? Clin Oral Investig, 21(8), 2619-2627, DOI: 10.1007/s00784-017-2063-9. PMID: 28154995.
Pachito, D. V., Latorraca, C. O. C., Riera, R. (2019). Efficacy of platelet-rich plasma for nontransfusion use: Overview of systematic reviews. Int J Clin Pract., 73(11), e13402. DOI: 10.1111/ ijcp.13402. PMID: 31408240.
Elghblawi, E. (2018). Platelet-rich plasma, the ultimate secret for youthful skin elixir and hair growth triggering. J Cosmet Dermatol, 17(3), 423-430, DOI: 10.1111/jocd.12404. PMID: 28887865.