Main monitoring performances of carbon exchange affecting the post-operating course cognitive dysfunction
PDF (Українська)

Keywords

cognitive dysfunction
anesthesia
lactate
pyruvate

How to Cite

Dubivska, S. (2020). Main monitoring performances of carbon exchange affecting the post-operating course cognitive dysfunction. Experimental and Clinical Medicine, 84(3), 54-58. https://doi.org/10.35339/ekm.2019.84.03.08

Abstract

In 130 patients of surgical departments of various profiles on the basis of the Kharkiv city clinical hospital of emergency and emergency medical care. prof. A.I. After applying general anesthesia, Meshchaninov determined the content of 2,3-diphosphoglycerate as an indicator of hypoxia depending on age. Surgery was performed under conditions of general multicomponent anesthesia with mechanical ventilation using propofol and fentanyl, sodium thiopental and fentanyl. Patients were divided into three groups: group I – 46 young patients (18–43 years old); Group II – 43 middle-aged patients (44–59 years old); ІІІ group – 41 elderly patients (60–80 years old). The main biochemical markers of carbohydrate metabolism — glucose, pyruvate, and lactate — were determined in the blood of patients. The studies conducted allowed us to integrally assess possible disorders of carbohydrate metabolism and characterize the features of the energy supply of the body of surgical patients at different periods of the disease, depending on age
https://doi.org/10.35339/ekm.2019.84.03.08
PDF (Українська)

References

Honskyi Ya.I., Maksymchuk T.P. (2019). Biokhimiia liudyny [Human biochemistry]. Ya.I. Honskyi (Ed.). Ternopil, 732 p. [in Ukrainian].

Rozhnova O.M., Sharapov V.I., Mayanskaya N.N. (2010). Biokhimiya krovi [Blood biochemistry]. Uspekhi sovremennogo yestestvoznaniya – The successes of modern science, № 2, рр. 47–48 [in Russian].

Sibіl M.G. (2015). Klinichna biokhimiya [Clinical biochemistry].

Lviv. : LDUFK, 228 p. [in Ukrainian].

Komisarenko S.V. (Eds.). (2013). Biokhimiya i biotekhnolohiya – suchasniy medytsyni [Biochemistry and biotechnology - modern medicine]. K.: FOP Moskalenko O.M., 704 p. [in Russian].

Gubsky Yu.I. (2007). Bioorhanichna khimiya [Bioorganic chemistry]. Yu.I. Gubsky (Ed.). Vinnytsya: Nova knyha, 732 p. [in Ukrainian].

Makarenko A.N., Savosko S.I. (2016). Vliyaniye tiopentala natriya na sostoyaniye energeticheskogo obmena v golovnom mozge [The effect of sodium thiopental on the state of energy metabolism in the brain]. Visnyk problem biolohiyi ta medytsyny – Bulletin of problems of biology and medicine, vol. 2, № 1 (128), pp. 56–59 [in Ukrainian].

Boykiv D.P., Ivankiv O.L., Kobylinska L.I. et al. (2002). Praktykum z biolohichnoyi khimiyi [Workshop on biological chemistry]. O.Ya. Sklyarov (Ed.). Kyyiv: «Zdorov'ya», 298 р. [in Ukrainian].

Marintsova N.G., Zhurakhivska L.R., Gubytska I.I. et al. (2009). Biolohichna khimiya [Biological chemistry]. Lviv: Vydavnytstvo Lʹvivsʹkoyi politekhniky, 324 p. [in Ukrainian]