Keywords
hypertension
excessive body weight
obesity
body mass index
How to Cite
Abstract
The article is devoted to the study of nesfatin-1 plasma level in hypertensive patients depending on excessive body weight or obesity presence. 83 patients with hypertension were examined. Excessive body weight was observed in 15.7% of hypertensive patients and 68.7 % had obesity. We found increased nesfatyn-1 activity in patients with hypertension that may indicate prohipertensive effect of adipocytokine. With the addition of excesssve body weight and obesity level nesfatyn-1 level significantly reduced, which could confirm its anorexigenic property, but in hypertensive patients with morbid obesity a direct correlation with anthropometric parameters was found. The data may indicate an active part of nesfatyn-1 in the pathogenesis and progression of hypertension and fat disorders.References
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