Prions and prion diseases: a modern look at the problem
PDF (Українська)

Keywords

prions
prion diseases
epidemiological control
perspectives of intravital diagnosis

How to Cite

Kotsar, O. V. (2020). Prions and prion diseases: a modern look at the problem. Experimental and Clinical Medicine, 79(2–3), 16-23. Retrieved from https://ecm.knmu.edu.ua/article/view/394

Abstract

A review devoted to prions - infectious proteins Proteinaceus infectious particle (PrP). They are the causative agents of the transmissible neurodegenerative diseases of animals and humans and are characterized by a long incubation period, a progressive course of the disease, pathological changes exclusively in the nervous tissue, in the absence of signs of infectious inflammation and immune response at the lethal end.
PDF (Українська)

References

Zavalishin I.A., Pohodina V.V., Kondakova L.I., Karmysheva V.Ya., Roichel V.M., Fokina H.I., Sobolev S.H. (2005). Prionnyie bolezni na sovremennom etape issledovania, provodimyie v Institute poliomielita i virusnikh encephalitov im. M. P. Chumakova RAMN [Prion diseases at the present stage and studies conducted at the Institute of Poliomyelitis and Viral Encephalitis. M.P. Chumakova RAMS]. Voprosy virusolohii – Questions of virology, № 3 (50), pp. 23-25 [in Russian].

Zavalishin I.A., Shitikova I.Ye., Hutchenko T.D. (2000). Priony i prionnyie bolezni [Prions and prion diseases]. Klinicheskaia mikrobiolohiia i antimikrobnaia khimioterapiia – Clinical microbiology and antimicrobial chemotherapy, № 2 (2), pp. 12–19 [in Russian].

Vorobiov A.A., Makarov V.V. (1997). Prionnyie infektsii: vazhneishiie meditsinskiie i veterinarnyie aspekty [Prion infections: the most important medical and veterinary aspects]. Vestnik RAMN – Herald. RAMN, №. 6, pp. 3–11 [in Russian].

Vassallo N., Herms J. (2003). Cellular prion protein function in copper homeostasis and redox signalling at the synapse. Journal of Neurochemistry, № 86, pp. 538–544.

Glenn L. Millhauser (2007). Cooper and prion protein: methods, structures, function and disease. Annual Reviews of Physical Chemistry, № 58, pp. 299–320.

Tatarnikova O.H., Orlov M.A., Bobkova N.V. (2015). Beta-amiloid i tau-belok struktura, vzaimodeistviie i prionopodobnyie svoistva [Beta-amyloid and tau-protein structure, interaction and prion-like properties]. Uspekhi biolohicheskoi khimii– Advances in biological chemistry, № 55, pp. 351–390 [in Russian].

Leonova Z.A. (2010). Prioni i prionnyie zabolevaniia [Prions and prion diseases]. Biulleten VSNTS SO RAMN – Bulletin VSSC of the RAMS, № 6 (76), pp. 169–174 [in Russian].

Kohan E.A. (2002). Prionnyie bolezni: sovremennyi vzhliad na problemu [Prion diseases: a modern view of the problem]. Arkhiv patolohii – Archive of pathology, № 6 (64), pp. 3–9. [in Russian].

Ter-Avanesian M.D. (1999). Priony: infektsionnyie belki s heneticheskimi svoistvami [Prions: infectious proteins with genetic properties]. Biokhimiia – Biochemistry, vol. 64, pp. 1638–1647 [in Russian].

Zuiev V.A. (1998). Priony – problema, kotoraia hrozit stat bedstviem [Prions – a problem that threatens to become a disaster]. Rossiyskiy meditsinskiy vestnik – The Russian medical bulletin, № 1 pp. 44–46 [in Russian].

Petr J. (2004). Prion i polost rta [Prion and mouth]. Novoie v stomatolohii – New in dentistry, № 6, pp. 77 [in Russian].

Shkundina I.S., Ter-Avanesian M.D. (2006). Priony [Prions]. Uspekhi biolohicheskoi khimii – Advances in biological chemistry, № 46, pp. 3–42 [in Russian].

Afanasieva E.H., Kushnirov V.V., Ter-Avanesian M.D. (2011). Mezhvidovaia peredacha prionov [Interspecies transfer of prions]. Uspekhi biolohicheskoi khimii – Advances in biological chemistr, № 51, pp. 3–24 [in Russian].

Zuiev V.A. (2014). Medlennyie infektsii [Slow infections]. Voprosy virusolohii – Questions of virology, № 5, pp. 5–12.

Gough K.C. Maddison B.C. (2010). Prion transmission. Prion, vol. 4, № 4, pp. 275–282.

Tsihanenko A.J. (2004). Priony i prionni hvoroby [Prions and prion diseases]. (3rd ed.). Kharkiv: Osnova, 80 pp.

Shevchenko A.V., Voronkova K.V., Pilaieva O.A., Ahmedova T.M. (2010). Sovremennyi vzhliad na problemu prionovykh bolezney [Modern view on the problem of prion diseases]. Russkii zhurnal detskoi nevrolohii – Russian Journal of Pediatric Neurology, vol. 5, № 2, pp. 31–42 [in Russian].

Lian N.A. (2015). Stenli Prusiner [Stanley Prusiner]. Allerholohiia i immunolohiia v pediatrii – Allergology and Immunology in Pediatrics, № 3, pp. 6–9 [in Russian].

Mudrikova U.V., Tustugasheva S.A. (2011). Prionnyie zabolevaniia krupnoho rohatoho skota [Prion diseases of cattle]. Tekhnika i tekhnologiya pishchevykh proizvodstv – Technology and technology of food production, № 1 (20), pp. 1–5 [in Russian].

Vlizlo V.V., Stadnik V.V., Maior H.J., Verbickii P.I., Stoika R.S. (2008). Identifikatsiia patolohicheskoho priona pri hubchatoobraznoi encephalopatii krupnoho rohatoho skota [Identification of pathological prion in spongiform encephalopathy of cattle]. Biotechnol. acta, № 2, pp. 75–80 [in Russian].

Fedorov Ye.I. (2001). Prionni hvoroby liudyny: diahnostychni aspekty problemy [Prion human diseases: diagnostic aspects of the problem]. Laboratorna diahnostika – Laboratory diagnostics, № 4, pp. 6–60 [in Ukrainian].

Sihurdson Christina J., Nilsson K. Peter, Hornemann S., Manco H., Polymenidou M., Schwartz P. et al. (2007). Prion strain discrimination using luminescent conjugated polymers. Nature methods, № 4, pp. 1023–1030.

Gaidash I.S., Flehontova V.V., Kazimirko N.K. Medychna virolohiia [Medical virology]. Lugansk, 357 p. [in Ukrainian].