Abstract
The paper presents the results of treatment of 58 patients with neuropathic and mixed SDS with the presence of wounds on the foot using topical BTP. It has been established that blood cells have a beneficial effect on the pathomorphosis of a wound, stimulating the development of granulation tissue, the source of which is type I collagen and ordered neoangiogenesis. Due to this, the formation of a full-fledged connective tissue and a full-fledged layer of the epithelium, contributing to quality wound healing in patients with complicated forms of SDS.References
Armstrong DG., Boulton AJM., Bus SA. (2017). Diabetic foot ulcers and their recurrence. N Engl J Med., № 376, рр. 2367–2375.
Zubair M., Malik A., Ahmad J. (2015). Diabetic Foot Ulcer: A Review. Am J Internal Med., vol. 3, № 2, рр. 28–49.
Gerasimov G.N. (2015). Rezultatyi modifitsirovannogo sposoba autodermoplastiki vyalo granuliruyuschih ran i troficheskih yazv nizhnih konechnostey [The results of the modified method autodermoplastiki sluggishly granulating wounds and trophic ulcers of the lower extremities]. Ekperimentalnaya i klinicheskaya meditsina – Experimental and Clinical Medicine, vol. 3, № 68, рр. 135–138 [in Russian].
Stryaphin V.V., Lishenko A.N. (2011). Hirurgicheskoe lechenie diabeticheskoy stopyi [Surgical treatment of diabetic foot]. Hirurgiya – Surgery, № 2, рр.73–78 [in Russian].
Grekova N.M., Bordunovskiy V.N., Gureva I.V. (2010). Diagnostika i hirurgicheskoe lechenie sindroma diabeticheskoy stopyi [Diagnosis and surgical treatment of diabetic foot syndrome]. Chelyabinsk, 112 p. [in Russian].
Ignatovich I.N., Kondratenko G.G., Nikulin D.D. (2013). Obosnovanie optimalnogo metoda lecheniya patsientov s neyroishemicheskoy formoy sindroma diabeticheskoy stopyi na osnovanii sravneniya otdalennyih rezultatov primeneniya razlichnyih metodov [Substantiation of the optimal method of treating patients with the neuroischemic form of diabetic foot syndrome based on a comparison of the long-term results of using various methods]. Novosti hirurgii – Surgery news, vol. 21, № 2, pp. 69–75 [in Russian].
Malik S.V., Ribalka Ya.V., OsIpov O.S., Verba A.V. (2017). Optimizatsiya likuvannya hvorih z privodu hronichnykh ran [Optimization of treatment for patients with chronic wounds]. Klinichna hirurgiya – Clinical surgery, № 10, рр. 49–50 [in Ukrainian].
Lipsky B.A., Aragón-Sánchez J., Diggle M. et al. (2016). International working group on the Diabetic Foot. IWGDF guidance on the diagnosis and management of foot infections in persons with diabetes. Diabetes Metab Res Rev, vol. 32 (Suppl. 1), pp. 45–74.
Prosyannikova N.V. (2013). Effektivnost lecheniya dlitelno nezazhivayuschih ran i yazv kozhi metodom autologichnoy bogatoy trombotsitami plazmyi [Efficiency of treatment of long-term non-healing wounds and ulcers of the skin by the method of autologous plasma-rich platelets]. Vrach skoroy pomoschi – Ambulance doctor. № 2, рр. 42–46 [in Russian].
Marx R.E., Carlson E.R., Eichstaedt R.M. et al. (1998). Platelet-rich plasma. Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radial Endod, vol. 85, pp. 638–646.
Paraskevich V.L. (2005). Primeneniye obogashchennoy trombotsitami i fibrinom plazmy krovi dlya zakrytiya posleoperatsionnykh ran [Use of blood plasma enriched with platelets and fibrin to close postoperative wounds]. Stomatologicheskiy zhurnal – Dental journal, № 6, pp. 53–55 [in Russian].