Abstract
In press
OsteoArthrosis (OA) is the most common joint disease in many populations and one of the main causes of incapacity for work among citizens of Ukraine, which usually manifests itself in people over 40 years of age. Therefore, the problem of OA has gained special importance and relevance due to its significant prevalence, rapid development of functional disorders and disability of people of different ages. Using the screening method, it was found that every second patient with a chronic disease of internal organs has OA, therefore the attention of scientists is focused on the issues of comorbidity and its influence on the course of the disease and the patient's satisfaction with the Quality of Life (QoL). A survey was conducted of 100 patients at the rheumatology department of the Chernivtsi city Clinical Hospital No.3, and 30 Practically Healthy Persons (PHP), who were given MOS SF-36 questionnaires (Medical Outcome Study Short Form-36) and KOOS (Knee injury and Osteoarthritis Outcome Score), in which patients had to answer questions based on their own thoughts and feelings about the questions asked. The results of the SF-36 survey indicate a significant decrease in indicators of the physical and psychological components of health in all groups of patients compared to PHP. These indicators are also significantly reduced in patients with arterial hypertension and with hypertension and type 2 diabetes compared to isolated OA. Evaluation of the results of the KOOS questionnaire indicated functional incapacity and expressed dissatisfaction with the quality of life. Based on the results of the study, a conclusion was made about the negative impact of concomitant pathology on the physical and psychological components of health and the need for routine use of the MOS SF-36 and KOOS questionnaires for early detection of QoL deterioration and for timely provision of necessary medical care.
Keywords: comorbidity, quality of life, SF-36, KOOS, osteoarthritis.
References
Valabhji J, Barron E, Pratt A, Hafezparast N, Dunbar-Rees R, Turner EB, et al. Prevalence of multiple long-term conditions (multimorbidity) in England: a whole population study of over 60 million people. J R Soc Med. 2024;117(3):104-17. DOI: 10.1177/01410768231206033. PMID: 37905525.
Arruda AL, Hartley A, Katsoula G, Smith GD, Morris AP, Zeggini E. Genetic underpinning of the comorbidity between type 2 diabetes and osteoarthritis. Am J Hum Genet. 2023;110(8):1304-18. DOI: 10.1016/j.ajhg.2023.06.010. PMID: 37433298.
Dolhopolov OV, Polishko VP, Yarova ML. Epidemiology of diseases of the musculoskeletal system in Ukraine for the period 1993-2017. Bulletin of orthopedics, traumatology and prosthetics. 2019;4:101-8. DOI: 10.37647/0132-2486-2019-103-4-96-104. [In Ukrainian].
GBD 2021 Osteoarthritis Collaborators. Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Rheumatol. 2023;5(9):508-22. DOI: 10.1016/S2665-9913(23)00163-7. PMID: 37675071.
Dubkova AH, Krylova AS, Tsymbaliuk TS. Modern aspects of treatment and monitoring of osteoarthritis of the hands. Ukrainian Journal of Rheumatology. 2020;85(3):1-10. DOI: 10.32471/rheumatology.2707-6970.85.16375. [In Ukrainian].
Corriero A, Giglio M, Soloperto R, Inchingolo F, Varrassi G, Puntillo F. Microbial Symphony: Exploring the Role of the Gut in Osteoarthritis-Related Pain. A Narrative Review. Pain Ther. 2024;13(3):409-33. DOI: 10.1007/s40122-024-00602-9. PMID: 38678155.
Kovalenko VM, Bortkevych OP. Comorbidity: definition, possible directions of diagnosis and treatment. Ukrainian Journal of Rheumatology. 2019;3(77):33-44. Available at: https://www.rheumatology.kiev.ua/wp/wp-content/uploads/2019/10/1149.pdf [in Ukrainian].
Nguyen H, Manolova G, Daskalopoulou C, Vitoratou S, Prince M, Prina AM. Prevalence of multimorbidity in community settings: A systematic review and meta-analysis of observational studies. J Comorb. 2019;9:2235042X19870934. DOI: 10.1177/2235042X19870934. PMID: 31489279.
Tan MMC, Barbosa MG, Pinho PJMR, Assefa E, Keinert AAM, Hanlon C, et al.; MUTUAL consortium. Determinants of multimorbidity in low- and middle-income countries: A systematic review of longitudinal studies and discovery of evidence gaps. Obes Rev. 2024;25(2):e13661. DOI: 10.1111/obr.13661. PMID: 38105610.
Lee C, Park YH, Cho B, Lee HA. A network-based approach to explore comorbidity patterns among community-dwelling older adults living alone. Geroscience. 2024;46(2):2253-64. DOI: 10.1007/s11357-023-00987-z. PMID: 37924440.
Dunlay SM, Chamberlain AM. Multimorbidity in Older Patients with Cardiovascular Disease. Curr Cardiovasc Risk Rep. 2016;10:3. DOI: 10.1007/s12170-016-0491-8. PMID: 27274775.
Kohn MD, Sassoon AA, Fernando ND. Classifications in Brief: Kellgren-Lawrence Classification of Osteoarthritis. Clin Orthop Relat Res. 2016;474(8):1886-93. DOI: 10.1007/s11999-016-4732-4. PMID: 26872913.
Order of the Ministry of Health of Ukraine No.384 щт 24 May 2012 "On the approval and implementation of medical and technological documents on the standardization of medical care for hypertension". In force on 20 Feb 2024. Verkhovna Rada (Parliament) of Ukraine. Legislation of Ukraine. Available at: https://zakon.rada.gov.ua/rada/show/v0384282-12 [In Ukrainian].
Halabitska IM. Life quality of patients with primary osteoarthritis in comorbidity with diseases accompanied by exocrine pancreatic insufficiency. Achievements of Clinical and Experimental Medicine. 2023;(4):40-5. DOI 10.11603/1811-2471.2023.v.i4.14298. [In Ukrainian].
Vitaloni M, Botto-van Bemden A, Sciortino Contreras RM, Scotton D, Bibas M, et al. Global management of patients with knee osteoarthritis begins with quality of life assessment: a systematic review. BMC Musculoskelet Disord. 2019;20(1):493. DOI: 10.1186/s12891-019-2895-3. PMID: 31656197.
Savvari P, Skiadas I, Papadakis SA, Psychogios V, Argyropoulou OD, Pastroudis AP, et al. The impact of moderate to severe osteoarthritis on the physical performance and quality of life: a cross-sectional study in Greek patients (PONOS study). BMC Musculoskelet Disord. 2023;24(1):651. DOI: 10.1186/s12891-023-06770-7. PMID: 37582740.
![Creative Commons License](http://i.creativecommons.org/l/by-nc-sa/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.