Keywords
granulation tissue
reticular allograft
How to Cite
Abstract
The experiment investigated the influence of preoperative remote gamma therapy on the features of the morphology of granulation tissue around the elements of the reticular allograft of the muscular-aponeurotic layer of the anterior abdominal wall. It is established that the use of preoperative remote gamma therapy distorts the maturation of granulation tissue. There is a probable increase in the percentage of fibroblasts and a decrease in lymphoid cells, polymorphonuclear leukocytes, macrophages, and plasma cells in the granulation tissue, mainly on the 5th and 7th day after surgery. Also on the 7th day of the study there was an increase in the specific volume of collagen fibers, their optical density, as well as the specific volume of blood vessels.
Keywords: preoperative gamma therapy, granulation tissue, reticular allograft.
References
Boiko, V.V., Savvi, S.O., Zhytetskyi, V.V., & Novykov, Ye.A. (2012). Prevention of eventrations after repeated surgical organs of the abdominal cavity. Kharkiv surgical school, 2(53), 11–12 [in Ukrainian].
Morar, I.K., Ivashchuk, O.I., Bodiaka, V.Iu. et al. (2017). Postoperative eventration. Clinical and experimental pathology, 16(1(59)), 177–181 [in Ukrainian].
Vorovskyi, O.O. (2013). Preventive abdominoplasty using a polypropylene prosthesis during primary laparotomy in elderly and senile patients as a method of prevention of postoperative abdominal wall defects. Clinical surgery, 11, 34–37 [in Ukrainian].
Zhebrovskiy, V.V., Kaminskiy, I.V., & Torotadze, N.N. (2010). The use of mesh implants in patients with eventration. Clinical surgery, 7, 13–17 [in russian].
Zhidetskiy, V.V. (2012). Prevention and surgical treatment of postoperative events. Medicine today and tomorrow, 2(55), 145–149 [in russian].
Petrovych, H.V. (2010). Histological aspects of the use of prolene allografts to prevent postoperative eventration in the experiment. Bukovynian Medical Bulletin, 14(1(53)), 128–130 [in Ukrainian].
Shaprynskyi, V.O., & Vorovskyi, O.O. (2011). Causes of evisceration and eventration in elderly and senile patients and methods of their surgical treatment. AML, vol. XVII, 49–52 [in Ukrainian].
Svinarenko, A.V. (2019). Radiobiological bases of radiation therapy for malignant tumors. Ukrainian Journal of Radiology, vol. XXVII, is. 4, 269–276 [in russian].
Tverdokhlib, I.V., & Maikov, I.I. (2010). Changes in the microcirculatory tract after plastic surgery of the experimental defect of the anterior abdominal wall in rats. Morphology, IV(2), 45–52 [in Ukrainian].
Morar, I.K., Ivashchuk, O.I., Davydenko, I.S., et al. (2015). Features of the formation of granulation tissue around the elements of the mesh implant of the anterior abdominal wall when using hyaluronic acid in the experiment. Clinical and experimental pathology, 2(52), 120–126 [in Ukrainian].
Morar, I.K., Ivashchuk, O.I., Davydenko, I.S., et al. (2015). Features of the morphology of granulation tissue around the elements of the mesh implant after performing plastic surgery of the anterior abdominal wall on the background of a malignant tumor process. Clinical anatomy and operative surgery, 14(3), 54–57 [in Ukrainian].
Morar, I.K., Ivashchuk, O.I., Bodiaka, V.Iu., Hushul, I.Ia., & Unhurian, V.P. (2016). Patent of Ukraine for utility model 106161, IPC A 61 В 17/00. Method of implanting reticular allograft into tissues of musculoskeletal aponeurotic layer of anterior abdominal wall of laboratory rat. Applicant and patent holder Bukovynian State Medical University, appl. No. 2015 06913; stated on 13 July 2015; published on 25 April 2016, bulletin No. 8 [in Ukrainian].
Korzhevskiy, D.E., & Gilyarov, A. V. (2010). Basics of histological technique. SPb: SpetsLit, pp. 96 [in russian].